human NKX3-1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

NKX3-1

Gene Name

NK3 homeobox 1

Gene ID

4824

Gene Synonyms

BAPX2; NKX3; NKX3.1; NKX3A

ORF Size

705 bp

RefSeq#

NM_006167

Gene Description

NKX3-1 encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene.

UniGene ID

Hs.55999

HGNC ID

HGNC:7838