human DUSP7 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-207441
Availability:
3-5 weeks
Name:
Ad-h-DUSP7-shRNA
This is an Adenovirus expressing shRNA for silencing of Human DUSP7.
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Product Info
- Knockdown
- >60% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- DUSP7
- Gene Name
- dual specificity phosphatase 7
- Gene ID
- 1849
- Gene Synonyms
- MKPX; PYST2
- ORF Size
- 1107 bp
- RefSeq#
- NM_001947
- Gene Description
- Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 (PubMed 19228121)).(supplied by OMIM, Dec 2009)
- UniGene ID
- Hs.591664
- HGNC ID
- HGNC:3073
Related Products
Product | Cat No. |
---|---|
AAV-h-DUSP7 | AAV-207441 |
AAV-m-DUSP7 | AAV-257552 |
Ad-h-DUSP7 | ADV-207441 |
Ad-m-DUSP7 | ADV-257552 |
AAV-h-DUSP7-shRNA | shAAV-207441 |
AAV-m-DUSP7-shRNA | shAAV-257552 |
Ad-m-DUSP7-shRNA | shADV-257552 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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