human MUTYH Over-expression AAV

Cat. No: AAV-216092

Availability: 3-5 weeks

Name: AAV-h-MUTYH

This is an AAV expressing Human MUTYH.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MUTYH
Gene Name: mutY DNA glycosylase
Gene ID: 4595
Gene Synonyms: MYH
ORF Size: 1608 bp
RefSeq#: BC003178
Gene Description: MUTYH encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.271353
HGNC ID: HGNC:7527