mouse NR1H4 Over-expression AAV

Cat. No: AAV-266036

Availability: 3-5 weeks

Name: AAV-m-NR1H4

This is an AAV expressing Mouse Nr1h4.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Nr1h4
Gene Name: nuclear receptor subfamily 1, group H, member 4
Gene ID: 20186
Gene Synonyms: AI957360; Fxr; HRR1; RIP14; Rxrip14
ORF Size: 1455 bp
RefSeq#: BC015261
Gene Description: Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.
UniGene ID: Mm.3095