mouse NR1H3 Over-expression AAV

Cat. No: AAV-266035

Availability: 3-5 weeks

Name: AAV-m-NR1H3

This is an AAV expressing Mouse Nr1h3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Nr1h3
Gene Name: nuclear receptor subfamily 1, group H, member 3
Gene ID: 22259
Gene Synonyms: AU018371; LXR; RLD1; Unr1
ORF Size: 1338 bp
RefSeq#: BC012646
Gene Description: Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8 (By similarity).
UniGene ID: Mm.22690