mouse PEO1 Over-expression AAV

Cat. No: AAV-268396

Availability: 3-5 weeks

Name: AAV-m-PEO1

This is an AAV expressing Mouse Twnk.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Twnk
Gene Name: twinkle mtDNA helicase
Gene ID: 226153
Gene Synonyms: D19Ertd626e; PEO; Peo1; Twinl
ORF Size: 2058 bp
RefSeq#: BC071195
Gene Description: Involved in mitochondrial DNA (mtDNA) metabolism. Could function as an adenine nucleotide-dependent DNA helicase. Function inferred to be critical for lifetime maintenance of mtDNA integrity. In vitro, forms in combination with POLG, a processive replication machinery, which can use double-stranded DNA (dsDNA) as template to synthesize single-stranded DNA (ssDNA) molecules. May be a key regulator of mtDNA copy number in mammals (By similarity).
UniGene ID: Mm.105585