mouse UHRF2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-275613
Availability:
3-5 weeks
Name:
AAV-m-UHRF2
This is an AAV expressing Mouse Uhrf2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Uhrf2
- Gene Name
- ubiquitin-like, containing PHD and RING finger domains 2
- Gene ID
- 109113
- Gene Synonyms
- 2310065A22Rik; AI426270; AW214556; D130071B19Rik; Nirf
- ORF Size
- 2412 bp
- RefSeq#
- BC060241
- Gene Description
- E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network. Through cooperative DNA and histone binding, may contribute to a tighter epigenetic control of gene expression in differentiated cells. Ubiquitinates cyclins, CCND1 and CCNE1, in an apparently phosphorylation-independent manner and induces G1 arrest. Also ubiquitinates PCNP leading to its degradation by the proteasome. Appears to contribute to tumorigenesis.
- UniGene ID
- Mm.313364
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