mouse STAM2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-273271
Availability:
3-5 weeks
Name:
AAV-m-STAM2
This is an AAV expressing Mouse Stam2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Stam2
- Gene Name
- signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
- Gene ID
- 56324
- Gene Synonyms
- 1200004O12Rik; 5730456G07Rik; BB145015; Hbp
- ORF Size
- 1572 bp
- RefSeq#
- BC013818
- Gene Description
- Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).
- UniGene ID
- Mm.263639
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