mouse RRM2B Over-expression AAV

Cat. No: AAV-271149

Availability: 3-5 weeks

Name: AAV-m-RRM2B

This is an AAV expressing Mouse Rrm2b.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Rrm2b
Gene Name: ribonucleotide reductase M2 B (TP53 inducible)
Gene ID: 382985
Gene Synonyms: p53R2
ORF Size: 1056 bp
RefSeq#: BC058103
Gene Description: Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.
UniGene ID: Mm.24738