mouse KLHL20 Over-expression AAV

Cat. No: AAV-262906

Availability: 3-5 weeks

Name: AAV-m-KLHL20

This is an AAV expressing Mouse Klhl20.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Klhl20
Gene Name: kelch-like 20
Gene ID: 226541
Gene Synonyms: AI504637; D930050H05Rik; Kleip; mKIAA4210
ORF Size: 1815 bp
RefSeq#: BC019571
Gene Description: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to its degradation by the proteasome, thereby acting as a negative regulator of apoptosis. Also acts as a regulator of endothelial migration during angiogenesis by controlling the activation of Rho GTPases.
UniGene ID: Mm.255165