human TMED10 Over-expression AAV

Cat. No: AAV-225672

Availability: 3-5 weeks

Name: AAV-h-TMED10

This is an AAV expressing Human TMED10.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TMED10
Gene Name: transmembrane p24 trafficking protein 10
Gene ID: 10972
Gene Synonyms: p23; P24(DELTA); p24d1; S31I125; S31III125; Tmp-21-I; TMP21
ORF Size: 660 bp
RefSeq#: BC001825
Gene Description: TMED10 is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. TMED10 has a pseudogene on chromosome 8.
UniGene ID: Hs.74137
HGNC ID: HGNC:16998