rat EEF2K Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-290418
Availability:
Immediate
Name:
AAV-r-EEF2K
This is an AAV expressing Rat Eef2k.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Rat
- Gene Symbol
- Eef2k
- Gene Name
- eukaryotic elongation factor-2 kinase
- Gene ID
- 25435
- Gene Synonyms
- SMEF2K
- ORF Size
- 2175 bp
- RefSeq#
- BC061825
- Gene Description
- Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.
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