mouse AGK Over-expression AAV

Cat. No: AAV-252228

Availability: 3-5 weeks

Name: AAV-m-AGK

This is an AAV expressing Mouse Agk.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Agk
Gene Name: acylglycerol kinase
Gene ID: 69923
Gene Synonyms: 2610037M15Rik; 6720408I04Rik; AI465370; Mulk
ORF Size: 1266 bp
RefSeq#: BC019145
Gene Description: Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
UniGene ID: Mm.32840