human NOX1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-216922
Availability:
3-5 weeks
Name:
AAV-h-NOX1
This is an AAV expressing Human NOX1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- NOX1
- Gene Name
- NADPH oxidase 1
- Gene ID
- 27035
- Gene Synonyms
- GP91-2; MOX1; NOH-1; NOH1
- ORF Size
- 1695 bp
- RefSeq#
- BC075015
- Gene Description
- Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.592227
- HGNC ID
- HGNC:7889
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