human NOSTRIN Over-expression AAV

Cat. No: AAV-216911

Availability: 3-5 weeks

Name: AAV-h-NOSTRIN

This is an AAV expressing Human NOSTRIN.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NOSTRIN
Gene Name: nitric oxide synthase trafficking
Gene ID: 115677
Gene Synonyms: DaIP2
ORF Size: 1521 bp
RefSeq#: BC093072
Gene Description: Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.(supplied by OMIM, Apr 2004)
UniGene ID: Hs.189780
HGNC ID: HGNC:20203