human STAR Over-expression AAV

Cat. No: AAV-224513

Availability: 3-5 weeks

Name: AAV-h-STAR

This is an AAV expressing Human STAR.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: STAR
Gene Name: steroidogenic acute regulatory protein
Gene ID: 6770
Gene Synonyms: STARD1
ORF Size: 858 bp
RefSeq#: BC010550
Gene Description: STAR plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.
UniGene ID: Hs.521535
HGNC ID: HGNC:11359