human MAP4K5 Over-expression AAV

Cat. No: AAV-214954

Availability: 3-5 weeks

Name: AAV-h-MAP4K5

This is an AAV expressing Human MAP4K5.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MAP4K5
Gene Name: mitogen-activated protein kinase kinase kinase kinase 5
Gene ID: 11183
Gene Synonyms: GCKR; KHS; KHS1; MAPKKKK5
ORF Size: 2541 bp
RefSeq#: BC036013
Gene Description: MAP4K5 encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
UniGene ID: Hs.130491
HGNC ID: HGNC:6867