human RBM9 Over-expression AAV

Cat. No: AAV-220891

Availability: 3-5 weeks

Name: AAV-h-RBM9

This is an AAV expressing Human RBFOX2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RBFOX2
Gene Name: RNA binding protein, fox-1 homolog 2
Gene ID: 23543
Gene Synonyms: dJ106I20.3; Fox-2; FOX2; fxh; HNRBP2; HRNBP2; RBM9; RTA
ORF Size: 1143 bp
RefSeq#: BC025281
Gene Description: RBFOX2 is one of several human genes similar to the C. elegans gene Fox-1. RBFOX2 encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.282998
HGNC ID: HGNC:9906