human OTC Over-expression AAV

Cat. No: AAV-217979

Availability: 3-5 weeks

Name: AAV-h-OTC

This is an AAV expressing Human OTC.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: OTC
Gene Name: ornithine carbamoyltransferase
Gene ID: 5009
Gene Synonyms: OCTD
ORF Size: 1065 bp
RefSeq#: BC107153
Gene Description: This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
UniGene ID: Hs.117050
HGNC ID: HGNC:8512