human SEC61A1 Over-expression AAV

Cat. No: AAV-222501

Availability: 3-5 weeks

Name: AAV-h-SEC61A1

This is an AAV expressing Human SEC61A1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SEC61A1
Gene Name: Sec61 translocon alpha 1 subunit
Gene ID: 29927
Gene Synonyms: HNFJ4; HSEC61; SEC61; SEC61A
ORF Size: 1431 bp
RefSeq#: BC156688
Gene Description: SEC61A1 belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits.
UniGene ID: Hs.518236
HGNC ID: HGNC:18276