human SDHD Over-expression AAV

Cat. No: AAV-222439

Availability: 3-5 weeks

Name: AAV-h-SDHD

This is an AAV expressing Human SDHD.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SDHD
Gene Name: succinate dehydrogenase complex subunit D
Gene ID: 6392
Gene Synonyms: CBT1; CII-4; CWS3; cybS; PGL; PGL1; QPs3; SDH4
ORF Size: 480 bp
RefSeq#: BC012603
Gene Description: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The subunit D protein is one of two integral membrane proteins anchoring the complex to the matrix side of the membrane. Mutations in SDHD have been linked to hereditary paraganglioma.
UniGene ID: Hs.356270
HGNC ID: HGNC:10683