human TYR Over-expression AAV

Cat. No: AAV-226938

Availability: 3-5 weeks

Name: AAV-h-TYR

This is an AAV expressing Human TYR.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TYR
Gene Name: tyrosinase
Gene ID: 7299
Gene Synonyms: ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3
ORF Size: 1134 bp
RefSeq#: BC027179
Gene Description: The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
UniGene ID: Hs.503555
HGNC ID: HGNC:12442