human HDAC3 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-210888
Availability:
3-5 weeks
Name:
AAV-h-HDAC3
This is an AAV expressing Human HDAC3.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- HDAC3
- Gene Name
- histone deacetylase 3
- Gene ID
- 8841
- Gene Synonyms
- HD3; RPD3; RPD3-2
- ORF Size
- 1287 bp
- RefSeq#
- BC000614
- Gene Description
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
- UniGene ID
- Hs.519632
- HGNC ID
- HGNC:4854
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