human CASP9 Over-expression AAV

Cat. No: AAV-204127

Availability: 3-5 weeks

Name: AAV-h-CASP9

This is an AAV expressing Human CASP9.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CASP9
Gene Name: caspase 9
Gene ID: 842
Gene Synonyms: APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56
ORF Size: 1251 bp
RefSeq#: BC006463
Gene Description: CASP9 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms.
UniGene ID: Hs.329502
HGNC ID: HGNC:1511