human GSK3B Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-210587
Availability:
3-5 weeks
Name:
AAV-h-GSK3B
This is an AAV expressing Human GSK3B.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- GSK3B
- Gene Name
- glycogen synthase kinase 3 beta
- Gene ID
- 2932
- ORF Size
- 1302 bp
- RefSeq#
- BC000251
- Gene Description
- GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.593022
- HGNC ID
- HGNC:4617
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