human MADCAM1 Over-expression AAV

Cat. No: AAV-214780

Availability: 3-5 weeks

Name: AAV-h-MADCAM1

This is an AAV expressing Human MADCAM1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MADCAM1
Gene Name: mucosal vascular addressin cell adhesion molecule 1
Gene ID: 8174
Gene Synonyms: MACAM1
ORF Size: 1221 bp
RefSeq#: BC142629
Gene Description: MADCAM1 is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined.
UniGene ID: Hs.102598
HGNC ID: HGNC:6765