human CLCNKA Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-205360
Availability:
3-5 weeks
Name:
AAV-h-CLCNKA
This is an AAV expressing Human CLCNKA.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- CLCNKA
- Gene Name
- chloride voltage-gated channel Ka
- Gene ID
- 1187
- Gene Synonyms
- ClC-K1; CLCK1; hClC-Ka
- ORF Size
- 2064 bp
- RefSeq#
- BC048282
- Gene Description
- CLCNKA is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.591533
- HGNC ID
- HGNC:2026
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