human DFNB31 Over-expression AAV

Cat. No: AAV-206900

Availability: 3-5 weeks

Name: AAV-h-DFNB31

This is an AAV expressing Human WHRN.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: WHRN
Gene Name: whirlin
Gene ID: 25861
Gene Synonyms: CIP98; DFNB31; PDZD7B; USH2D; WI
ORF Size: 2724 bp
RefSeq#: BC142614
Gene Description: DFNB31 is thought to function in the organization and stabilization of sterocilia elongation and actin cystoskeletal assembly, based on studies of the related mouse gene. Mutations in this gene have been associated with autosomal recessive non-syndromic deafness and Usher Syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
UniGene ID: Hs.93836
HGNC ID: HGNC:16361