human PDCD10 Over-expression AAV

Cat. No: AAV-218433

Availability: 3-5 weeks

Name: AAV-h-PDCD10

This is an AAV expressing Human PDCD10.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PDCD10
Gene Name: programmed cell death 10
Gene ID: 11235
Gene Synonyms: CCM3; TFAR15
ORF Size: 639 bp
RefSeq#: BC016353
Gene Description: PDCD10 encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.
UniGene ID: Hs.478150
HGNC ID: HGNC:8761