human KLK2 Over-expression AAV

Cat. No: AAV-213290

Availability: 3-5 weeks

Name: AAV-h-KLK2

This is an AAV expressing Human KLK2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KLK2
Gene Name: kallikrein related peptidase 2
Gene ID: 3817
Gene Synonyms: hGK-1; hK2; KLK2A2
ORF Size: 786 bp
RefSeq#: BC005196
Gene Description: KLK2 encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. KLK2 is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants.
UniGene ID: Hs.515560
HGNC ID: HGNC:6363