human IRGM Over-expression AAV

Cat. No: AAV-212416

Availability: 3-5 weeks

Name: AAV-h-IRGM

This is an AAV expressing Human IRGM.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: IRGM
Gene Name: immunity related GTPase M
Gene ID: 345611
Gene Synonyms: IFI1; IRGM1; LRG-47; LRG47
ORF Size: 537 bp
RefSeq#: BC128168
Gene Description: IRGM encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.
UniGene ID: Hs.652148
HGNC ID: HGNC:29597