human LILRB5 Over-expression AAV

Cat. No: AAV-213938

Availability: 3-5 weeks

Name: AAV-h-LILRB5

This is an AAV expressing Human LILRB5.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: LILRB5
Gene Name: leukocyte immunoglobulin like receptor B5
Gene ID: 10990
Gene Synonyms: CD85C; LIR-8; LIR8
ORF Size: 1773 bp
RefSeq#: BC025704
Gene Description: LILRB5 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.655338
HGNC ID: HGNC:6609