Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

EIF4E

Gene Name

eukaryotic translation initiation factor 4E

Gene ID

1977

Gene Synonyms

AUTS19; CBP; eIF-4E; EIF4E1; EIF4EL1; EIF4F

ORF Size

654 bp

RefSeq#

BC035166

Gene Description

EIF4E is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of cellular mRNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the mRNA. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. Three transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.249718

HGNC ID

HGNC:3287