human DBN1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-206622
Availability:
3-5 weeks
Name:
AAV-h-DBN1
This is an AAV expressing Human DBN1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- DBN1
- Gene Name
- drebrin 1
- Gene ID
- 1627
- Gene Synonyms
- D0S117E
- ORF Size
- 1950 bp
- RefSeq#
- BC007281
- Gene Description
- DBN1 is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
- UniGene ID
- Hs.130316
- HGNC ID
- HGNC:2695
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