human CXCL12 Over-expression AAV

Cat. No: AAV-206331

Availability: 3-5 weeks

Name: AAV-h-CXCL12

This is an AAV expressing Human CXCL12.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CXCL12
Gene Name: C-X-C motif chemokine ligand 12
Gene ID: 6387
Gene Synonyms: IRH; PBSF; SCYB12; SDF1; TLSF; TPAR1
ORF Size: 270 bp
RefSeq#: BC039893
Gene Description: CXCL12 encodes a stromal cell-derived alpha chemokine member of the intercrine family. CXCL12 product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.522891
HGNC ID: HGNC:10672