human BCL2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-202036
Availability:
3-5 weeks
Name:
AAV-h-BCL2
This is an AAV expressing Human BCL2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- BCL2
- Gene Name
- B-cell CLL/lymphoma 2
- Gene ID
- 596
- Gene Synonyms
- Bcl-2;
- ORF Size
- 720 bp
- RefSeq#
- BC027258
- Gene Description
- BCL2 encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
- UniGene ID
- Hs.150749
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