human CNOT7 Over-expression AAV

Cat. No: AAV-205614

Availability: 3-5 weeks

Name: AAV-h-CNOT7

This is an AAV expressing Human CNOT7.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CNOT7
Gene Name: CCR4-NOT transcription complex subunit 7
Gene ID: 29883
Gene Synonyms: CAF-1; CAF1; Caf1a; hCAF-1
ORF Size: 741 bp
RefSeq#: BC007315
Gene Description: CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
UniGene ID: Hs.598387
HGNC ID: HGNC:14101