Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

ATP7A

Gene Name

ATPase copper transporting alpha

Gene ID

538

Gene Synonyms

DSMAX; MK; MNK; SMAX3

ORF Size

4500 bp

RefSeq#

BC156437

Gene Description

ATP7A encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans-Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked cutis laxa, and occipital horn syndrome.

UniGene ID

Hs.496414

HGNC ID

HGNC:869