Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Srebf2

Gene Name

sterol regulatory element binding factor 2

Gene ID

20788

Gene Synonyms

AI608257; bHLHd2; lop13; nuc; SREBP-2; SREBP2; SREBP2gc

ORF Size

3393 bp

RefSeq#

BC167259

Gene Description

Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity). Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes.

UniGene ID

Mm.38016