human TMEM189-UBE2V1 Adenovirus

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

TMEM189-UBE2V1

Gene Name

TMEM189-UBE2V1 readthrough

Gene ID

387522

Gene Synonyms

CROC-1B; CROC1B; KUA-UEV

ORF Size

1113 bp

RefSeq#

BC172339

Gene Description

The TMEM189-UEV mRNA is an infrequent but naturally occurring read-through transcript of the neighboring TMEM189 and UBE2V1 genes. Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein produced by this transcript has UEV1 B domains but the protein is localized to the cytoplasm rather than to the nucleus. The significance of this read-through mRNA and the function of its protein product has not yet been determined.

UniGene ID

Hs.

HGNC ID

HGNC:33521