Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PRDM1

Gene Name

PR/SET domain 1

Gene ID

639

Gene Synonyms

BLIMP1; PRDI-BF1

ORF Size

2076 bp

RefSeq#

BC103835

Gene Description

PRDM1 encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.

UniGene ID

Hs.436023

HGNC ID

HGNC:9346