Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

YWHAQ

Gene Name

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta

Gene ID

10971

Gene Synonyms

14-3-3; 1C5; HS1

ORF Size

738 bp

RefSeq#

BC093019

Gene Description

YWHAQ product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. YWHAQ is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.

UniGene ID

Hs.74405

HGNC ID

HGNC:12854