Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SAE1

Gene Name

SUMO1 activating enzyme subunit 1

Gene ID

10055

Gene Synonyms

AOS1; HSPC140; SUA1; UBLE1A

ORF Size

1041 bp

RefSeq#

BC000344

Gene Description

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 (PubMed 9920803)).(supplied by OMIM, Mar 2010)

UniGene ID

Hs.515500

HGNC ID

HGNC:30660