Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

TIAL1

Gene Name

TIA1 cytotoxic granule associated RNA binding protein like 1

Gene ID

7073

Gene Synonyms

TCBP; TIAR

ORF Size

759 bp

RefSeq#

BC030025

Gene Description

TIAL1 is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing.

UniGene ID

Hs.501203

HGNC ID

HGNC:11804