Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

OLIG2

Gene Name

oligodendrocyte lineage transcription factor 2

Gene ID

10215

Gene Synonyms

BHLHB1; bHLHe19; OLIGO2; PRKCBP2; RACK17

ORF Size

972 bp

RefSeq#

BC036245

Gene Description

OLIG2 encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.

UniGene ID

Hs.176977

HGNC ID

HGNC:9398