Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

NEK1

Gene Name

NIMA related kinase 1

Gene ID

4750

Gene Synonyms

NY-REN-55; SRPS2; SRPS2A; SRTD6

ORF Size

3570 bp

RefSeq#

BC114491

Gene Description

NEK1 is a serine/threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.481181

HGNC ID

HGNC:7744