Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

NR4A2

Gene Name

nuclear receptor subfamily 4 group A member 2

Gene ID

4929

Gene Synonyms

HZF-3; NOT; NURR1; RNR1; TINUR

ORF Size

1797 bp

RefSeq#

BC009288

Gene Description

NR4A2 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

UniGene ID

Hs.563344

HGNC ID

HGNC:7981