Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

CABLES1

Gene Name

Cdk5 and Abl enzyme substrate 1

Gene ID

91768

Gene Synonyms

CABL1; CABLES; HsT2563; IK3-1

ORF Size

1107 bp

RefSeq#

BC037218

Gene Description

CABLES1 encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.11108

HGNC ID

HGNC:25097