Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

CDT1

Gene Name

chromatin licensing and DNA replication factor 1

Gene ID

81620

Gene Synonyms

DUP; RIS2

ORF Size

1641 bp

RefSeq#

BC000137

Gene Description

CDT1 is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein.

UniGene ID

Hs.122908

HGNC ID

HGNC:24576