Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

CHN1

Gene Name

chimerin 1

Gene ID

1123

Gene Synonyms

ARHGAP2; CHN; DURS2; NC; RHOGAP2

ORF Size

1380 bp

RefSeq#

BC011393

Gene Description

CHN1 encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane's retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

UniGene ID

Hs.654534

HGNC ID

HGNC:1943